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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
APLF
All Species:
3.94
Human Site:
T228
Identified Species:
10.83
UniProt:
Q8IW19
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IW19
NP_775816.1
511
56956
T228
K
D
K
S
Q
L
N
T
T
Q
Q
G
R
R
Q
Chimpanzee
Pan troglodytes
XP_515525
303
34195
C47
E
Q
D
T
G
E
K
C
K
N
T
D
Q
E
E
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_538525
510
57035
V227
I
C
K
D
K
T
Q
V
N
I
T
Q
Q
G
G
Cat
Felis silvestris
Mouse
Mus musculus
Q9D842
499
54950
T220
Q
R
S
G
K
A
G
T
C
E
D
R
T
P
G
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514287
555
61656
S256
K
G
R
S
V
P
V
S
Q
Q
P
G
R
K
R
Chicken
Gallus gallus
XP_419335
514
57457
E223
H
M
E
S
L
K
S
E
V
S
I
L
Q
R
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001099159
262
29285
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
A8JR14
255
27987
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_788055
674
74378
R337
P
K
K
A
K
T
S
R
S
Q
R
G
S
A
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
57.9
N.A.
72.2
N.A.
60
N.A.
N.A.
41.2
44.7
N.A.
23.4
N.A.
21.3
N.A.
N.A.
28.1
Protein Similarity:
100
58.9
N.A.
81.4
N.A.
74.7
N.A.
N.A.
57.2
61.8
N.A.
33
N.A.
31.5
N.A.
N.A.
43.7
P-Site Identity:
100
0
N.A.
6.6
N.A.
6.6
N.A.
N.A.
33.3
13.3
N.A.
0
N.A.
0
N.A.
N.A.
20
P-Site Similarity:
100
26.6
N.A.
20
N.A.
26.6
N.A.
N.A.
60
40
N.A.
0
N.A.
0
N.A.
N.A.
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
12
0
12
0
0
0
0
0
0
0
12
0
% A
% Cys:
0
12
0
0
0
0
0
12
12
0
0
0
0
0
0
% C
% Asp:
0
12
12
12
0
0
0
0
0
0
12
12
0
0
0
% D
% Glu:
12
0
12
0
0
12
0
12
0
12
0
0
0
12
12
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
12
0
12
12
0
12
0
0
0
0
34
0
12
23
% G
% His:
12
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
12
0
0
0
0
0
0
0
0
12
12
0
0
0
0
% I
% Lys:
23
12
34
0
34
12
12
0
12
0
0
0
0
12
23
% K
% Leu:
0
0
0
0
12
12
0
0
0
0
0
12
0
0
0
% L
% Met:
0
12
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
12
0
12
12
0
0
0
0
0
% N
% Pro:
12
0
0
0
0
12
0
0
0
0
12
0
0
12
0
% P
% Gln:
12
12
0
0
12
0
12
0
12
34
12
12
34
0
12
% Q
% Arg:
0
12
12
0
0
0
0
12
0
0
12
12
23
23
12
% R
% Ser:
0
0
12
34
0
0
23
12
12
12
0
0
12
0
0
% S
% Thr:
0
0
0
12
0
23
0
23
12
0
23
0
12
0
0
% T
% Val:
0
0
0
0
12
0
12
12
12
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _